Lung neuroendocrine tumors: pathological characteristics

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Advances in neuroendocrine lung tumors.

Pulmonary neuroendocrine (NE) tumors include a spectrum of tumors from the low-grade typical carcinoid (TC) and intermediate-grade atypical carcinoid (AC) to the high-grade large-cell neuroendocrine carcinoma (LCNEC) and small-cell carcinoma (SCLC). Nodular NE proliferations ≥ 0.5 cm are classified as carcinoid tumors and smaller ones are called tumorlets. When NE cell hyperplasia and tumorlets...

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BACKGROUND Only one tumor site is usually biopsied to determine the histologic features of that patient's entire tumor burden. We hypothesized that there are significant histologic and functional differences in primary neuroendocrine tumors (NETS) and their nodal or organ metastases. We also hypothesized that limited tumor sampling could lead to erroneous assumptions about the tumor's histologi...

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ژورنال

عنوان ژورنال: Journal of Thoracic Disease

سال: 2017

ISSN: 2072-1439,2077-6624

DOI: 10.21037/jtd.2017.01.59